University of Zagreb School of Medicine

The role of scientific evidence in transfusion treatment. Researches that have changed therapeutic viewpoints: model of acceptable transfusion threshold; and model of hemodilution. Clinical decision on transfusion therapy and volume replacement based on scientific evidence, with special reference to specific entities in surgery, internal medicine, paediatrics, oncology and gynaecology. Methodology of assessing transfusion therapy efficacy and justifiability as a scientific task in the process of improvement of transfusion treatment quality and safety. Transfusion treatment side effects (vein-to-vein haemovigilance). Alternative modalities of transfusion treatment.

The topics proposed will be adjusted to the group of students; an additional topic can also be introduced, depending on the specific interests of the students.

Final seminar: critical analysis of a scientific article on the topic (journal club).

• Anthes E. Evidence-based medicine: Save blood, save lives. Nature. 2015; 520: 24-26.
• Kaufman RM, Djulbegovic B,Gernsheimer T, i sur. Platelet Transfusion: A Clinical Practice guideline From the AABB Platelet Transfusion: A Clinical Practice Guideline From the AABB  Ann Intern Med. 2015;162(3):205-213.
• Lozano M Cid J Transfusion medicine as of 2014. F1000Prime Rep 2014; 6:105-110.
• Szczepiorkowski ZM, Dunbar NM, Transfusion guidelines: when to transfuse. Hematology 2013; 2013:638-644
• Roback JD Evidence-Based Guidelines for Blood Transfusion. Infusion Nurses Society, 2012; 35: 187-190.2
• Roback JD, Caldwell S, Carson J i sur. Evidence-based practice guidelines for plasma transfusion, Transfusion 2010; 50: 12278-1239_
• Skodlar J, Majerić-Kogler V i sur. Klinička transfuzijska praksa: priručnik za liječnike, Ministarstvo zdravstva RH, Zagreb 2002.
• Baze podataka (Ovid): EBM Reviews-ACP Journal Club i Cochrane baze: Controlled Trials Register, Database of Systematic Reviews, Database of Abstracts of Reviews of Effectivness
• Practical Transfusion Medicine, Fourth Edition urednici Murphy MF, Derwood H. Pamphilon DH,  Heddle NM, Wiley Online Library 2013.
• Blood Banking and Transfusion Medicine: Basic Principles and Practice Second Edition. urednici Hillyer CD, Silberstein LE, Ness PM, Anderson KC, Roback JD. Elsevier, 2007.

Lectures and seminars

Oral exam